Most of the uterine cancer risk factors linked to endometrial cancer come from too much exposure to the hormone estrogen.
The following factors increase the risk of endometrial cancer:
- Being overweight
- Diet high in animal fats
- Family history of colon cancer (hereditary nonpolyposis colon cancer or Lynch syndrome)
- Family history of endometrial cancer
- Not being physically active
- Older age
- Past radiation therapy to the pelvis
- Personal history of atypical endometrial hyperplasia
- Personal history of breast cancer
- Personal history of ovarian cancer
- Taking things that affect hormone levels like estrogen after menopause or Tamoxifen
- Type 2 diabetes
Lowering Your Risk
Maintaining a healthy weight through diet and exercise may help to lower the risk areas you can control. Avoid smoking and excessive alcohol consumption.
Managing your health, like staying on top of diabetes, can also lower your risk of cancer.
Hormone therapy may affect your risk. According to the American Cancer Society, taking estrogen alone may increase your risk of developing endometrial cancer. However, taking progestin in addition to estrogen may lower your risk of cancer.